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Home » ICMR, AIIMS Rule Out COVID-19 Vaccine Link to Sudden Deaths in Young Adults

ICMR, AIIMS Rule Out COVID-19 Vaccine Link to Sudden Deaths in Young Adults

Ananya Pattnaik by Ananya Pattnaik
July 2, 2025
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Extensive studies conducted by the Indian Council of Medical Research (ICMR) and AIIMS, New Delhi, have conclusively found no direct connection between COVID-19 vaccines and sudden deaths among young adults in India.


Instead, the findings indicate that lifestyle, genetics, pre-existing conditions, and post-COVID complications are the primary contributors to these fatalities.

Addressing growing public concern, the Government of India released data from two high-level investigations, emphasizing the safety and effectiveness of COVID-19 vaccines administered in the country. These investigations were led by ICMR’s National Institute of Epidemiology (NIE) and AIIMS, in collaboration with the National Centre for Disease Control (NCDC).

Key Findings from the Studies

1. ICMR’s Retrospective Case-Control Study

The first major study, conducted between May and August 2023, analyzed cases from 47 tertiary care hospitals across 19 states and Union Territories. Titled “Factors associated with unexplained sudden deaths among adults aged 18-45 years in India”, it focused on seemingly healthy individuals who died suddenly between October 2021 and March 2023.

The findings clearly show that COVID-19 vaccination was not a risk factor for sudden unexplained deaths. Instead, several other contributing causes—such as obesity, smoking, lack of exercise, and undiagnosed cardiac issues—were found to be more relevant.

2. AIIMS-ICMR Prospective Study

The second ongoing study, “Establishing the cause in sudden unexplained deaths in young”, is being conducted by AIIMS, New Delhi, with support from ICMR. This forward-looking research is investigating the physiological causes behind sudden deaths in real-time.

Preliminary results suggest heart attacks (myocardial infarction) remain the leading cause. Moreover, genetic mutations have been frequently identified in cases previously considered “unexplained.” Significantly, no drastic changes in the patterns of causes were observed compared to pre-pandemic years.

Scientific Consensus & Public Health Message

Top medical experts have warned that speculative claims linking vaccines to sudden deaths are not just misleading—they’re dangerous. They stress that such misinformation could contribute to vaccine hesitancy, jeopardizing public health efforts.

The Government of India has reiterated its commitment to evidence-based public health research, reassuring citizens of its intent to address all concerns through transparent and scientific inquiry.

The studies collectively affirm that COVID-19 vaccines in India are safe and not associated with unexplained deaths. The focus now shifts to raising awareness about cardiac health, early screening, and promoting healthy lifestyle habits among young adults.

Tags: AIIMSCOVID vaccinesICMRIndia
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